SCHEMBL5174159

SCHEMBL5174159

Fc1ccc(-c2ccc3ccccc3n2)c(F)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 11/20 0.57
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
GAA P10253 1/20 0.53
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
HPGD P15428 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
KMO O15229 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932125 1.00 AR (0.57) ARNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL31438887 0.98 AR (0.56) ARNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL28959133 0.98 AR (0.56) ARNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL10864858 0.85 AR (0.58) ARNPC1RAB9ASMN1; SMN2KDM4E
2-Picolinic Acid SCHEMBL20184181 0.82 KMO (0.52) ARNPC1RAB9ASMN1; SMN2KDM4E
2-Picolinic Acid SCHEMBL29510673 0.82 KMO (0.52) ARNPC1RAB9ASMN1; SMN2KDM4E
2-Picolinic Acid SCHEMBL28290126 0.82 KMO (0.52) ARNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL29746148 0.82 AR (0.54) ARNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL6087610 0.82 AR (0.54) ARNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL27912074 0.81 AR (0.59) ARNPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106946943-A Ionic type iridium phosphorescent complexes and preparation method thereof 昆明贵金属研究所 2017-07-14 CN claimed
CN-113745420-B Organic light emitting device 乐金显示有限公司 2024-04-02 CN disclosed
CN-106946943-A Ionic type iridium phosphorescent complexes and preparation method thereof 昆明贵金属研究所 2017-07-14 CN disclosed
CN-106946943-A Ionic type iridium phosphorescent complexes and preparation method thereof 昆明贵金属研究所 2017-07-14 CN disclosed
EP-1820227-A1 METAL COMPLEXES AND THEIR USE AS THE EMITTING CONSTITUENT IN ELECTRONIC COMPONENTS, IN PARTICULAR IN ELECTROLUMINESCENT DISPLAY DEVICES MERCK PATENT GmbH (DE) 2007-08-22 EP disclosed
WO-2006061182-A1 METAL COMPLEXES AND THEIR USE AS THE EMITTING CONSTITUENT IN ELECTRONIC COMPONENTS, IN PARTICULAR IN ELECTROLUMINESCENT DISPLAY DEVICES MERCK PATENT GMBH (DE) 2006-06-15 WO disclosed
US-6835469-B2 Phosphorescent compounds and devices comprising the same THE UNIVERSITY OF SOUTHERN CALIFORNIA 2004-12-28 US disclosed
WO-2003033617-A1 PHOSPHORESCENT COMPOUNDS AND DEVICES COMPRISING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2003-04-24 WO disclosed
US-20030072964-A1 Phosphorescent compounds and devices comprising the same TRUSTEES OF PRINCETON UNIVERSITY, THE 2003-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030072964-A1 Phosphorescent compounds and devices comprising the same NUDC, ORC3, PAICS AR 3237/4885NPC1 3932/4885RAB9A 2256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.