Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766999 | 0.90 | TSHR (0.49) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL2638629 | 0.90 | TSHR (0.55) | TSHRALDH1A1THRB | |
| SCHEMBL10908446 | 0.89 | TSHR (0.50) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL2916918 | 0.85 | TSHR (0.50) | TSHRALDH1A1THRB | |
| SCHEMBL134372 | 0.80 | TSHR (0.55) | TSHRALDH1A1THRB | |
| SCHEMBL19680511 | 0.78 | TSHR (0.63) | TSHRALDH1A1THRB | |
| SCHEMBL9818660 | 0.78 | TSHR (0.53) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL3004876 | 0.78 | TSHR (0.53) | TSHRALDH1A1THRB | |
| SCHEMBL12572340 | 0.77 | FABP3 (0.45) | TSHRTHRB | |
| SCHEMBL11475397 | 0.77 | TSHR (0.52) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462079-B1 | Dental composition | G C DENTAL IND CORP (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-20040254261-A1 | Dental composition | GC CORPORATION (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1462079-A1 | Dental composition | GC Corporation (JP) | 2004-09-29 | — | — | EP | disclosed |