SCHEMBL134372

SCHEMBL134372

C=C(C)C(=O)OCC(COC(=O)C(=C)C)OP(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.39
ENPP2 Q13822 5/20 0.33
LPAR3 Q9UBY5 3/20 0.32
LPAR1 Q92633 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SMPD1 P17405 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14368416 0.93 TSHR (0.49) TSHRALDH1A1THRBENPP2LPAR3
SCHEMBL2867414 0.91 TSHR (0.50) TSHRALDH1A1THRBENPP2
SCHEMBL11659922 0.91 TSHR (0.50) TSHRALDH1A1THRBENPP2LPAR3
SCHEMBL766999 0.90 TSHR (0.49) TSHRALDH1A1THRBENPP2
SCHEMBL2638629 0.89 TSHR (0.55) TSHRALDH1A1THRB
SCHEMBL3283176 0.89 TSHR (0.47) TSHRALDH1A1THRBENPP2LPAR3
SCHEMBL26108009 0.89 TSHR (0.47) TSHRALDH1A1THRBENPP2LPAR3
SCHEMBL15752949 0.86 TSHR (0.45) TSHRTHRBENPP2LPAR3LPAR1
SCHEMBL11475397 0.86 TSHR (0.52) TSHRALDH1A1THRB
SCHEMBL401685 0.84 TSHR (0.63) TSHRALDH1A1THRBSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118879207-A High temperature resistant acrylate adhesives 伊利诺斯工具制品有限公司 2024-11-01 CN claimed
CN-117503616-B Self-adhesive resin water heater with self-curing stability and preparation method thereof 日照沪鸽生物材料有限公司 2024-10-22 CN claimed
EP-3265046-B1 STABILIZED CALCIUM PHOSPHATE AND METHODS OF FORMING SAME Modern Ideas LLC (US) 2024-09-04 EP claimed
US-20240279516-A1 HIGH TEMPERATURE RESISTANT ACRYLIC ADHESIVE ILLINOIS TOOL WORKS INC. (US) 2024-08-22 US claimed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US claimed
CN-117943055-A Hydrolytic filler and preparation method and application thereof 中国石油化工股份有限公司 2024-04-30 CN claimed
WO-2023078367-A1 SECONDARY BATTERY 珠海冠宇电池股份有限公司 2023-05-11 WO claimed
CN-114094102-A Secondary battery 珠海冠宇电池股份有限公司 2022-02-25 CN claimed
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2021-02-25 US claimed
CN-106726623-B Single-component photocuring composite material with fluoride ion release characteristic for dental restoration and application thereof 日照沪鸽生物材料有限公司 2020-12-04 CN claimed
EP-1881010-A1 Polymerizable compositions containing salts of barbituric acid derivatives 3M Innovative Properties Company (US) 2008-01-23 EP claimed
WO-2007079166-A1 DENTAL COMPOSITIONS WITH SURFACE-TREATED FILLER FOR SHELF STABILITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-12 WO claimed
US-20060270751-A1 Adhesive composition with decreased polarity upon polymerization 3M DEUTSCHLAND GMBH (DE) 2006-11-30 US claimed
EP-1498098-B1 Adhesive composition with decreased polarity upon polymerization 3M ESPE AG (DE) 2006-05-03 EP claimed
WO-2005004819-A1 ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION 3M ESPE AG (DE) 2005-01-20 WO claimed
EP-1498098-A1 Adhesive composition with decreased polarity upon polymerization 3M ESPE AG (DE) 2005-01-19 EP claimed
EP-1282388-A4 POLYMERIZABLE DISPERSANT KERR CORP (US) 2003-06-04 EP claimed
EP-1282388-A1 POLYMERIZABLE DISPERSANT Kerr Corporation (US) 2003-02-12 EP claimed
US-6359090-B1 FOR PRODUCING CURED ARTICLES HAVING REDUCED SHRINKAGE, A LOWER COEFFICIENT OF THERMAL EXPANSION AND IMPROVED PHYSICAL PROPERTIES KERR CORPORATION 2002-03-19 US claimed
WO-2001087242-A1 POLYMERIZABLE DISPERSANT KERR CORPORATION (US) 2001-11-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 TSHR 4596/4885ALDH1A1 1481/4885THRB 4522/4885
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES NCAPH, RCC1, NCAPD2 TSHR 4596/4885ALDH1A1 1481/4885THRB 4522/4885
US-20060270751-A1 Adhesive composition with decreased polarity upon polymerization PTK2, PHOSPHO1, ITGA1 TSHR 4650/4885ALDH1A1 1541/4885THRB 3495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.