Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901678 | 0.92 | TSHR (0.81) | TSHRCYP19A1KLK7MEN1CRHBP | |
| SCHEMBL873430 | 0.86 | TSHR (1.00) | TSHRAKR1B1CYP19A1ALDH1A1KLK7 | |
| SCHEMBL10309729 | 0.85 | TSHR (0.70) | TSHRCYP19A1HPGDKLK7MEN1 | |
| SCHEMBL9626909 | 0.85 | TSHR (0.70) | TSHRCA2CAMK2AAKR1B1CYP19A1 | |
| SCHEMBL14010060 | 0.85 | TSHR (0.70) | TSHRCYP19A1ALDH1A1LMNAKLK7 | |
| Hydrochloric Acid SCHEMBL27332250 | 0.85 | TSHR (0.96) | TSHRAKR1B1CYP19A1ALDH1A1KLK7 | |
| SCHEMBL27883126 | 0.85 | TSHR (0.96) | TSHRAKR1B1CYP19A1ALDH1A1KLK7 | |
| SCHEMBL10369206 | 0.83 | TSHR (0.68) | TSHRCYP19A1LMNAGAAHTT | |
| SCHEMBL29197989 | 0.83 | TSHR (0.68) | TSHRCYP19A1ALDH1A1HSD17B10GAA | |
| SCHEMBL27484257 | 0.83 | TSHR (0.93) | TSHRAKR1B1CYP19A1ALDH1A1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791901-A2 | STABILIZATION OF ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006024611-A2 | STABILIZATION OF ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-03-09 | — | — | WO | disclosed |