Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901678 | 0.90 | TSHR (0.81) | TSHRMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL10309729 | 0.83 | TSHR (0.70) | TSHRMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL5175026 | 0.83 | TSHR (0.76) | TSHRMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL14010060 | 0.83 | TSHR (0.70) | TSHRMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL9626909 | 0.83 | TSHR (0.70) | TSHRMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL10369206 | 0.81 | TSHR (0.68) | TSHRMEN1KMT2ACYP19A1KLK7 | |
| SCHEMBL873430 | 0.81 | TSHR (1.00) | TSHRCYP19A1KLK7POLBMAPT | |
| SCHEMBL317876 | 0.80 | TSHR (0.66) | TSHRKMT2AKLK7TDP1SMN1; SMN2 | |
| SCHEMBL11630772 | 0.80 | TSHR (0.65) | TSHRMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL11147997 | 0.79 | CYP19A1 (0.46) | TSHRCYP19A1POLBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417285-B | Isomanka key intermediate and preparation method thereof | 苏中药业集团股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-117417285-A | Isomanka key intermediate and preparation method thereof | 苏中药业集团股份有限公司 | 2024-01-19 | — | — | CN | disclosed |