SCHEMBL517512

SCHEMBL517512

OC(CCCCCCCCOCc1ccccc1)CCCCCCCCOCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
TSHR P16473 1/20 0.48
GBA1 P04062 2/20 0.47
UGCG Q16739 2/20 0.47
GBA2 Q9HCG7 2/20 0.47
MMP3 P08254 3/20 0.44
MMP8 P22894 3/20 0.44
MMP9 P14780 2/20 0.44
EPHX2 P34913 1/20 0.44
MMP1 P03956 2/20 0.44
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
ADRB3 P13945 1/20 0.43
TRPA1 O75762 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608254 1.00 CA1 (0.50) CA1L3MBTL1TDP1CA2CA7
SCHEMBL25238062 1.00 CA1 (0.50) CA1L3MBTL1TDP1CA2CA7
SCHEMBL19032486 1.00 CA1 (0.50) CA1L3MBTL1TDP1CA2CA7
SCHEMBL23117118 1.00 CA1 (0.50) CA1L3MBTL1TDP1CA2CA7
SCHEMBL3429104 0.92 CSNK1E (0.49) CA1L3MBTL1TDP1CA2CA7
SCHEMBL22749478 0.92 CSNK1E (0.49) CA1L3MBTL1TDP1CA2CA7
SCHEMBL6026038 0.92 CSNK1E (0.49) CA1L3MBTL1TDP1CA2CA7
SCHEMBL31362251 0.92 CSNK1E (0.49) CA1L3MBTL1TDP1CA2CA7
SCHEMBL15153556 0.92 CSNK1E (0.49) CA1L3MBTL1TDP1CA2CA7
SCHEMBL31362254 0.92 CSNK1E (0.49) CA1L3MBTL1TDP1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674856-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
EP-2788006-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2026-01-07 EP disclosed
EP-3254672-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2025-08-20 EP disclosed
US-12364762-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-22 US disclosed
US-12350338-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-08 US disclosed
US-12343398-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-01 US disclosed
US-12239709-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-03-04 US disclosed
EP-4481047-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2024-12-25 EP disclosed
US-20240398956-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2024-12-05 US disclosed
US-20240285768-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2024-08-29 US disclosed
US-9012498-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-04-21 US disclosed
US-9012498-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-04-21 US disclosed
EP-2788006-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2014-10-15 EP disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 US disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 US disclosed
WO-2013086354-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-06-13 WO disclosed
EP-2575764-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2013-04-10 EP disclosed
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-02-02 US disclosed
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-02-02 US disclosed
WO-2011153493-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2011-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, CETP, APOB CA1 3362/4885L3MBTL1 1399/4885TDP1 1576/4885
US-12343398-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP CA1 3391/4885L3MBTL1 1228/4885TDP1 1779/4885
US-20240398956-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP CA1 3391/4885L3MBTL1 1228/4885TDP1 1779/4885
US-12350338-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP CA1 3391/4885L3MBTL1 1228/4885TDP1 1779/4885
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP CA1 3391/4885L3MBTL1 1228/4885TDP1 1779/4885
US-12239709-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP CA1 3391/4885L3MBTL1 1228/4885TDP1 1779/4885
US-20240285768-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP CA1 3391/4885L3MBTL1 1228/4885TDP1 1779/4885
US-12364762-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP CA1 3391/4885L3MBTL1 1228/4885TDP1 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.