Styrene

Styrene

SCHEMBL5175176

C=CC(=C)C.C=CC=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.51
ALDH1A1 P00352 5/20 0.50
TSHR P16473 2/20 0.50
MAOB P27338 1/20 0.45
TDP1 Q9NUW8 2/20 0.40
GLA P06280 1/20 0.40
MAPK1 P28482 2/20 0.39
LMNA P02545 2/20 0.39
TRPA1 O75762 1/20 0.39
ALOX5 P09917 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 2/20 0.38
RECQL P46063 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
ALOX15 P16050 1/20 0.38
PSMD14 O00487 1/20 0.38
TP53 P04637 2/20 0.37
HDAC3 O15379 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4359280 0.94 CYP3A4 (0.51) CYP3A4ALDH1A1TSHRMAOBTDP1
SCHEMBL4359283 0.94 CYP3A4 (0.51) CYP3A4ALDH1A1TSHRMAOBTDP1
SCHEMBL27513947 0.93 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRMAOBTDP1
SCHEMBL11174960 0.87 CYP3A4 (0.53) CYP3A4ALDH1A1TSHRMAOBTDP1
Cinnamaldehyde SCHEMBL28777987 0.87 ALDH1A1 (0.56) CYP3A4ALDH1A1TSHRMAOBTDP1
Styrene SCHEMBL35198 0.87 ALDH1A1 (0.61) CYP3A4ALDH1A1TSHRTDP1GLA
Styrene SCHEMBL27291 0.87 ALDH1A1 (0.61) CYP3A4ALDH1A1TSHRTDP1GLA
Styrene SCHEMBL1616325 0.87 ALDH1A1 (0.61) CYP3A4ALDH1A1TSHRTDP1GLA
Styrene SCHEMBL3311197 0.87 ALDH1A1 (0.61) CYP3A4ALDH1A1TSHRTDP1GLA
Styrene SCHEMBL6526981 0.87 ALDH1A1 (0.61) CYP3A4ALDH1A1TSHRTDP1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106457754-A Multilayer film comprising an odor barrier layer having sound dampening properties 霍利斯特股份有限公司 2017-02-22 CN disclosed
EP-1629045-B1 INJECTION-MOLDABLE TRANSPARENT THERMOPLASTIC ELASTOMER, SHAPED ARTICLE AND METHOD GLS CORP (US) 2007-05-30 EP disclosed
EP-1629045-A1 INJECTION-MOLDABLE TRANSPARENT THERMOPLASTIC ELASTOMER, SHAPED ARTICLE AND METHOD GLS Corporation (US) 2006-03-01 EP disclosed
US-6984688-B2 Injection-moldable transparent thermoplastic elastomer GLS CORP (US) 2006-01-10 US disclosed
WO-2004099310-A1 INJECTION-MOLDABLE TRANSPARENT THERMOPLASTIC ELASTOMER GLS CORPORATION (US) 2004-11-18 WO disclosed
US-20040220323-A1 Injection-moldable transparent thermoplastic elastomer COLORMATRIX HOLDINGS, INC. 2004-11-04 US disclosed
US-6486229-B1 Radiation curable hot melt adhesive NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2002-11-26 US disclosed