Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898542 | 0.87 | AR (0.50) | ARTAS2R14SLC22A12RORC | |
| SCHEMBL4905143 | 0.87 | AR (0.50) | ARTAS2R14SLC22A12RORC | |
| SCHEMBL4898546 | 0.87 | AR (0.50) | ARTAS2R14SLC22A12RORC | |
| SCHEMBL5185000 | 0.82 | AR (0.43) | ARTAS2R14SLC22A12PGR | |
| SCHEMBL5175028 | 0.79 | AR (0.42) | ARTAS2R14SLC22A12RORC | |
| SCHEMBL5120802 | 0.76 | AR (0.49) | ARTAS2R14SLC22A12PGR | |
| SCHEMBL24632242 | 0.76 | AR (0.49) | ARTAS2R14SLC22A12 | |
| SCHEMBL5175018 | 0.75 | AR (0.47) | ARTAS2R14RORCPGR | |
| SCHEMBL5176077 | 0.75 | AR (0.47) | ARTAS2R14RORCPGR | |
| SCHEMBL3289362 | 0.74 | AR (0.55) | ARTAS2R14SLC22A12PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747193-A1 | BENZONITRILE DERIVATIVES TO TREAT MUSCULOSKELETAL FRAILTY | Pfizer Products Incorporated (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005108351-A1 | BENZONITRILE DERIVATIVES TO TREAT MUSCULOSKELETAL FRAILTY | PFIZER PRODUCTS INC. (US) | 2005-11-17 | — | — | WO | disclosed |