Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768685 | 0.91 | NR1H3 (0.50) | TTRCES1NR1H3NR1H2LMNA | |
| SCHEMBL6000324 | 0.82 | TTR (0.64) | TTRCES1NR1H3NR1H2LMNA | |
| SCHEMBL31107472 | 0.82 | TTR (0.64) | TTRCES1NR1H3NR1H2LMNA | |
| SCHEMBL2604394 | 0.81 | TTR (0.56) | TTRCES1LMNAMAPTDRD2 | |
| SCHEMBL30542242 | 0.79 | TTR (0.54) | TTRCES1LMNAMAPTDRD2 | |
| SCHEMBL3797403 | 0.79 | TTR (0.54) | TTRCES1LMNAMAPTDRD2 | |
| SCHEMBL11882604 | 0.77 | TTR (0.52) | TTRCES1LMNAMAPTDRD2 | |
| SCHEMBL19792450 | 0.76 | TTR (0.47) | TTRCES1NR1H3NR1H2LMNA | |
| SCHEMBL19932851 | 0.75 | NR1H3 (0.33) | TTRCES1NR1H3NR1H2DRD2 | |
| SCHEMBL13629815 | 0.75 | NR1H3 (0.38) | TTRCES1NR1H3NR1H2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018217538-A1 | SYNTHESIS OF SUBSTITUTED ACRIDINES | UNIVERSITY OF ST. THOMAS (US) | 2018-11-29 | — | — | WO | disclosed |
| US-9526769-B2 | Macrocylic oximyl hepatitis C protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-8940688-B2 | Fluorinated tripeptide HCV serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2015-01-27 | — | — | US | disclosed |
| US-20140349297-A1 | FLUORESCENT DYES BASED ON ACRIDINE AND ACRIDINIUM DERIVATIVES | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| US-20140349297-A1 | FLUORESCENT DYES BASED ON ACRIDINE AND ACRIDINIUM DERIVATIVES | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| WO-2013093481-A1 | FLUORESCENT DYES BASED ON ACRIDINE AND ACRIDINIUM DERIVATIVES | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2013-06-27 | — | — | WO | disclosed |
| US-8426360-B2 | Carbocyclic oxime hepatitis C virus serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8361958-B2 | Oximyl HCV serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| EP-1509601-B1 | FLUORESCENT DETECTION OF PEROXIDASE ENZYMES | LUMIGEN INC (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8268776-B2 | mixture of cytochrome P450 monooxygenase inhibitor and protease inhibitor for anti-hepatitis C viral treatment; including other active drugs as interferon, ribavarin, and adamantine | ENANTA PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20070026334-A1 | Electrophotographic photoreceptor and image forming apparatus including the same | SHARP KABUSHIKI KAISHA (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-0984281-B1 | A homogeneous assay for determining analyte | DADE BEHRING MARBURG GMBH (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1418430-A2 | A homogeneous assay for determining analyte | Dade Behring Marburg GmbH (DE) | 2004-05-12 | — | — | EP | disclosed |
| EP-0984282-B1 | Particles having an incorporated composition comprising a chemiluminescent compound | DADE BEHRING MARBURG GMBH (DE) | 2003-07-30 | — | — | EP | disclosed |
| US-6406913-B1 | ANALYZING A SAMPLE, TREATING WITH ENERGY AND DETECTION A SIGNAL | DADE BEHRING MARBURG GMBH (DE) | 2002-06-18 | — | — | US | disclosed |
| EP-0515194-B1 | Assay methods utilizing induced luminescence | DADE BEHRING MARBURG GMBH (DE) | 2001-10-31 | — | — | EP | disclosed |
| US-6251581-B1 | MIXTURE OF SUSPENDABLE PARTICLES, ONE TYPE IS CHEMILUMINESCENT COMPOUND CAPABLE OF REACTING WITH SINGLET OXYGEN, THE OTHER TYPE IS PHOTOSENSITIZER WHICH IS CAPABLE OF ACTIVATING OXYGEN TO ITS SINGLET STATE | DADE BEHRING MARBURG GMBH (DE) | 2001-06-26 | — | — | US | disclosed |
| EP-0984282-A2 | Particles having an incorporated composition comprising a chemiluminescent compound | Dade Behring Marburg GmbH (DE) | 2000-03-08 | — | — | EP | disclosed |
| EP-0984281-A2 | A homogeneous assay for determining analyte | Dade Behring Marburg GmbH (DE) | 2000-03-08 | — | — | EP | disclosed |
| EP-0515194-A2 | Assay methods utilizing induced luminescence | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-11-25 | — | — | EP | disclosed |