Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31107472 | 1.00 | TTR (0.64) | TTRCES1NR1H3NR1H2EPHX2 | |
| SCHEMBL13310851 | 0.88 | CES1 (0.71) | TTRCES1NR1H3NR1H2EPHX2 | |
| SCHEMBL16127516 | 0.82 | TTR (0.75) | TTRCES1NR1H3NR1H2EPHX2 | |
| SCHEMBL5175484 | 0.82 | TTR (0.50) | TTRCES1NR1H3NR1H2RAB9A | |
| SCHEMBL13039623 | 0.78 | TTR (0.69) | TTRCES1EPHX2RAB9ATRPA1 | |
| SCHEMBL30077375 | 0.78 | TTR (0.69) | TTRCES1EPHX2RAB9ATRPA1 | |
| SCHEMBL28252336 | 0.78 | CES1 (1.00) | TTRCES1EPHX2RAB9ATRPA1 | |
| SCHEMBL12059596 | 0.78 | TTR (0.69) | TTRCES1NR1H3NR1H2EPHX2 | |
| SCHEMBL126628 | 0.78 | CES1 (1.00) | TTRCES1EPHX2RAB9ATRPA1 | |
| SCHEMBL2521380 | 0.77 | CES1 (0.88) | TTRCES1EPHX2RAB9ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106077-A1 | Pin1-Modulating compounds and methods of use thereof | PINTEX PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | US | claimed |
| EP-1551396-A1 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Pintex Pharmaceuticals, Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| WO-2005007123-A2 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PINTEX PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | claimed |
| US-20040214872-A1 | Pin1-modulating compounds and methods of use thereof | PINTEX PHARMACEUTICALS, INC. | 2004-10-28 | — | — | US | claimed |
| WO-2004028535-A1 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PINTEX PHARMACEUTICALS, INC. (US) | 2004-04-08 | — | — | WO | claimed |
| US-20230183391-A1 | BIOMASS DERIVED DIKETONES AS EFFICIENT VISIBLE LIGHT PHOTOINITIATORS | BOWLING GREEN STATE UNIVERSITY (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230121798-A1 | MATERIAL FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-04-20 | — | — | US | disclosed |
| US-20150129861-A1 | ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME | FUJIFILM CORPORATION (JP) | 2015-05-14 | — | — | US | disclosed |
| US-20060106077-A1 | Pin1-Modulating compounds and methods of use thereof | PINTEX PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | US | disclosed |
| EP-1551396-A1 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Pintex Pharmaceuticals, Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2005007123-A2 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PINTEX PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |
| US-20040214872-A1 | Pin1-modulating compounds and methods of use thereof | PINTEX PHARMACEUTICALS, INC. | 2004-10-28 | — | — | US | disclosed |
| WO-2004028535-A1 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PINTEX PHARMACEUTICALS, INC. (US) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106077-A1 | Pin1-Modulating compounds and methods of use thereof | PIN1, FKBP14, PIN4 | TTR 4402/4885CES1 2801/4885NR1H3 1101/4885 |
| US-20040214872-A1 | Pin1-modulating compounds and methods of use thereof | PIN1, FKBP14, PIN4 | TTR 4402/4885CES1 2801/4885NR1H3 1101/4885 |
| US-20230121798-A1 | MATERIAL FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND | OR10J3, CDH1, ICAM1 | TTR 697/4885CES1 3473/4885NR1H3 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.