⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180025 | 0.78 | — | — | |
| SCHEMBL1532379 | 0.78 | — | — | |
| SCHEMBL25285279 | 0.76 | — | — | |
| SCHEMBL14991649 | 0.75 | — | — | |
| SCHEMBL2738465 | 0.72 | — | — | |
| SCHEMBL6653346 | 0.72 | TP53 (0.31) | — | |
| SCHEMBL841668 | 0.71 | — | — | |
| SCHEMBL1086192 | 0.71 | — | — | |
| SCHEMBL1996074 | 0.69 | — | — | |
| SCHEMBL21060829 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824850-A2 | SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION | Nycomed GmbH (DE) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006061380-A2 | SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION | ALTANA PHARMA AG (DE) | 2006-06-15 | — | — | WO | disclosed |