Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5174346 | 0.84 | KDM4E (0.42) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5175198 | 0.84 | KDM4E (0.51) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5174762 | 0.83 | MAPT (0.45) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5176748 | 0.81 | MAPT (0.58) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5175693 | 0.81 | KDM4E (0.52) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5176689 | 0.80 | KDM4E (0.44) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5174945 | 0.78 | GAA (0.45) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5175851 | 0.76 | CXCR4 (0.63) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5174651 | 0.76 | BACE1 (0.44) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL5175577 | 0.74 | RAB9A (0.50) | KDM4EMAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | claimed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | claimed |
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | disclosed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | KRT18, ALDH7A1, MKI67 | KDM4E 160/4885MAPT 1080/4885KMT2A 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.