Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 9/20 | 0.65 |
| ▸ | ITPR1 | Q14643 | 5/20 | 0.65 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.65 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.56 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19712146 | 1.00 | ITPR3 (0.65) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL220555 | 0.98 | ITPR3 (0.67) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL237183 | 0.98 | ITPR3 (0.67) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL219762 | 0.98 | ITPR3 (0.67) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL6664274 | 0.96 | ITPR3 (0.74) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL11233751 | 0.96 | ITPR3 (0.60) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL7171543 | 0.96 | ITPR3 (0.60) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL5175173 | 0.95 | ITPR3 (0.58) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL267294 | 0.95 | ITPR3 (0.58) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL267295 | 0.95 | ITPR3 (0.58) | ITPR3ITPR1ITPR2INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000263-B2 | Inositol polyphosphate 2-kinase genes and uses thereof | DOW AGROSCIENCES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| EP-1786901-B1 | INOSITOL POLYPHOSPHATE 2-KINASE GENES AND USES THEREOF | DOW AGROSCIENCES LLC (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-1786901-A2 | INOSITOL POLYPHOSPHATE 2-KINASE GENES AND USES THEREOF | Dow AgroSciences LLC (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006029296-A2 | INOSITOL POLYPHOSPHATE 2-KINASE GENES AND USES THEREOF | DOW AGROSCIENCES LLC (US) | 2006-03-16 | — | — | WO | disclosed |