Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MVD | P53602 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132609 | 0.80 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL3029332 | 0.77 | CYP3A4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL7132612 | 0.76 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL4454861 | 0.76 | MEN1 (0.34) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL3988371 | 0.76 | MEN1 (0.34) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL11178967 | 0.73 | CHRNB2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL10937857 | 0.73 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL19631272 | 0.73 | TP53 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL1642999 | 0.73 | LPAR3 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL7873122 | 0.73 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789078-A1 | PULMONARY DELIVERY OF A NERVE AGENT NEUTRALIZING ENZYME | Nexia Biotechnologies, Inc. (CA) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006017935-A1 | PULMONARY DELIVERY OF A NERVE AGENT NEUTRALIZING ENZYME | NEXIA BIOTECHNOLOGIES, INC. (CA) | 2006-02-23 | — | — | WO | disclosed |