Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CD69 | Q07108 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.42 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.42 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177592 | 1.00 | LMNA (0.54) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL31068056 | 0.90 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL25788683 | 0.90 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL4399197 | 0.90 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL25788745 | 0.90 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL2817867 | 0.88 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL14400226 | 0.88 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL12153379 | 0.88 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL6329776 | 0.87 | LMNA (0.57) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL6329767 | 0.87 | LMNA (0.57) | LMNAKMT2AALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499743-B1 | MEANS AND METHODS FOR DETECTING ENDOGLYCOSIDASE ACTIVITY | AZ UNIV AMSTERDAM (NL) | 2007-06-06 | — | — | EP | disclosed |
| EP-1359227-A1 | Methods for detecting endoglycosidase activity | Academisch Ziekenhuis bij de Universiteit van Amsterdam (NL) | 2003-11-05 | — | — | EP | disclosed |