Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31492742 | 0.87 | CYP2C19 (0.44) | PPM1BPTPN1PPP1CCCYP2C19EPHX1 | |
| SCHEMBL13204690 | 0.82 | PPM1B (0.38) | PPM1BPTPN1PPP1CCCYP2C19CHRNB2 | |
| SCHEMBL13222141 | 0.82 | PPM1B (0.38) | PPM1BPTPN1PPP1CCCYP2C19CHRNB2 | |
| SCHEMBL20995893 | 0.81 | PPM1B (0.52) | PPM1BPTPN1PPP1CCCYP2C19CHRNB2 | |
| SCHEMBL14029643 | 0.78 | EPHX1 (0.40) | PPM1BPTPN1PPP1CCEPHX1TRPM8 | |
| SCHEMBL4617338 | 0.78 | EPHX1 (0.40) | PPM1BPTPN1PPP1CCEPHX1TRPM8 | |
| SCHEMBL14544418 | 0.78 | EPHX1 (0.40) | PPM1BPTPN1PPP1CCEPHX1TRPM8 | |
| SCHEMBL14029653 | 0.78 | EPHX1 (0.40) | PPM1BPTPN1PPP1CCEPHX1TRPM8 | |
| SCHEMBL14047812 | 0.78 | EPHX1 (0.40) | PPM1BPTPN1PPP1CCEPHX1TRPM8 | |
| SCHEMBL14029612 | 0.78 | EPHX1 (0.40) | EPHX1TRPM8TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1331861-C | Production of dihydronepetalactone by hydrogenation of nepetalactone | DU PONT (US) | 2007-08-15 | — | — | CN | disclosed |
| EP-1490351-B1 | PRODUCTION OF DIHYDRONEPETALACTONE BY HYDROGENATION OF NEPETALACTONE | DU PONT (US) | 2007-06-06 | — | — | EP | disclosed |
| US-7067677-B2 | Production of dihydronepetalactone by hydrogenation of nepetalactone | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-27 | — | — | US | disclosed |
| CN-1642935-A | Production of dihydronepetalactone by hydrogenation of nepetalactone | DU PONT (US) | 2005-07-20 | — | — | CN | disclosed |
| EP-1490351-A1 | PRODUCTION OF DIHYDRONEPETALACTONE BY HYDROGENATION OF NEPETALACTONE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20030225290-A1 | Production of dihydronepetalactone by hydrogenation of nepetalactone | 1,4Group, Inc. | 2003-12-04 | — | — | US | disclosed |
| WO-2003084946-A1 | PRODUCTION OF DIHYDRONEPETALACTONE BY HYDROGENATION OF NEPETALACTONE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225290-A1 | Production of dihydronepetalactone by hydrogenation of nepetalactone | MME, NQO1, GNPAT | PPM1B 3904/4885PTPN1 4753/4885PPP1CC 2874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.