Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PPP5C | P53041 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14544860 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL14029625 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL14047804 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL2776355 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL14047812 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL14544418 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL14029653 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL5008061 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL4617338 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA | |
| SCHEMBL14544417 | 1.00 | EPHX1 (0.40) | EPHX1PPP5CKDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165506-A1 | PULEGANIC ACID INSECT REPELLENT | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165506-A1 | PULEGANIC ACID INSECT REPELLENT | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-27 | — | — | US | disclosed |
| US-7435851-B2 | Puleganic amides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-14 | — | — | US | disclosed |
| WO-2007041306-A1 | PULEGANIC ACID INSECT REPELLENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041307-A1 | PULEGANIC AMIDES AS INSECT REPELLANTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20070077262-A1 | Puleganic acid insect repellents | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-04-05 | — | — | US | disclosed |
| US-20070077263-A1 | N-Substituted or N,N-disubstituted-2-isopropyl-5-methylcyclopentanecarboxamides, e.g., N,N-diethyl- or N-benzyl-; useful as a topical treatment for skin, such as a repellant for insects and arthropods | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165506-A1 | PULEGANIC ACID INSECT REPELLENT | CUTA, PPT1, PCCA | EPHX1 1693/4885PPP5C 485/4885KDM4E 3829/4885 |
| US-20070077263-A1 | N-Substituted or N,N-disubstituted-2-isopropyl-5-methylcyclopentanecarboxamides, e.g., N,N-diethyl- or N-benzyl-; useful as a topical treatment for skin, such as a repellant for insects and arthropods | CUTA, PNN, NAPEPLD | EPHX1 1023/4885PPP5C 1125/4885KDM4E 652/4885 |
| US-20070077262-A1 | Puleganic acid insect repellents | CUTA, PPT1, PCCA | EPHX1 1669/4885PPP5C 536/4885KDM4E 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.