Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985687 | 0.76 | CACNA1G (0.39) | BRD4TSHRMAPTGAASMN1; SMN2 | |
| SCHEMBL2552391 | 0.76 | GAA (0.40) | TSHRMAPTGAASMN1; SMN2 | |
| SCHEMBL4927895 | 0.75 | SETD7 (0.42) | BRD4TSHR | |
| SCHEMBL20820009 | 0.75 | — | — | |
| SCHEMBL20820011 | 0.75 | — | — | |
| SCHEMBL22578791 | 0.74 | BRD4 (0.38) | BRD4SRD5A1 | |
| SCHEMBL25726128 | 0.73 | BRD4 (0.33) | BRD4 | |
| SCHEMBL29942704 | 0.73 | TSHR (0.54) | TSHRMAPTGAASMN1; SMN2ALOX5 | |
| SCHEMBL29942458 | 0.73 | TSHR (0.54) | TSHRMAPTGAASMN1; SMN2ALOX5 | |
| SCHEMBL2636205 | 0.71 | DPP4 (0.39) | TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |