Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.65 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179892 | 1.00 | DNM1 (0.65) | DNM1DGKAPAMKDM5APRSS1 | |
| SCHEMBL5179680 | 0.95 | DNM1 (0.66) | DNM1DGKAPAMPRSS1PRSS2 | |
| SCHEMBL5179838 | 0.95 | DNM1 (0.66) | DNM1DGKAPAMPRSS1PRSS2 | |
| SCHEMBL5178165 | 0.91 | DNM1 (0.74) | DNM1DGKAPAMKDM5APRSS1 | |
| SCHEMBL8522015 | 0.91 | DNM1 (0.74) | DNM1DGKAPAMKDM5APRSS1 | |
| SCHEMBL4245473 | 0.91 | DNM1 (0.72) | DNM1DGKAPAMPRSS1PRSS2 | |
| SCHEMBL432806 | 0.91 | DNM1 (0.72) | DNM1DGKAPAMPRSS1PRSS2 | |
| SCHEMBL8398314 | 0.91 | DNM1 (0.72) | DNM1DGKAPAMPRSS1PRSS2 | |
| SCHEMBL8394729 | 0.91 | DNM1 (0.72) | DNM1DGKAPAMPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL10784814 | 0.89 | DNM1 (0.70) | DNM1DGKAPAMPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927174-B1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MEDIGENE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| EP-0927174-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MediGene Oncology GmbH (DE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011082-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-03-19 | — | — | WO | disclosed |