Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179274 | 0.97 | DNM1 (0.47) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5188960 | 0.97 | DNM1 (0.47) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5177904 | 0.93 | DNM1 (0.48) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5180334 | 0.93 | DNM1 (0.48) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5179132 | 0.89 | DNM1 (0.55) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5179258 | 0.86 | DNM1 (0.45) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5178169 | 0.86 | DNM1 (0.45) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL8444937 | 0.86 | DNM1 (0.47) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5179404 | 0.86 | DNM1 (0.47) | DNM1DGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL5180036 | 0.84 | DNM1 (0.41) | DNM1DGKAGNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927174-B1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MEDIGENE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| EP-0927174-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MediGene Oncology GmbH (DE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011082-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-03-19 | — | — | WO | disclosed |