Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006782 | 0.79 | TLR7 (0.55) | TLR7TLR8NUDT1 | |
| SCHEMBL8113946 | 0.78 | TLR7 (0.54) | TLR7NUDT1 | |
| SCHEMBL1538304 | 0.70 | TLR7 (0.59) | TLR7TLR8NUDT1 | |
| Water SCHEMBL29421423 | 0.69 | TLR7 (0.58) | TLR7TLR8NUDT1 | |
| Water SCHEMBL622142 | 0.69 | TLR7 (0.58) | TLR7TLR8NUDT1 | |
| SCHEMBL24024902 | 0.67 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL8123096 | 0.64 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL29606142 | 0.64 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL22898779 | 0.64 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL1891398 | 0.63 | TLR7 (0.35) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765310-A2 | A MIXTURE FOR TRANSDERMAL DELIVERY OF LOW AND HIGH MOLECULAR WEIGHT COMPOUNDS | ORYXE (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006041538-A2 | A MIXTURE FOR TRANSDERMAL DELIVERY OF LOW AND HIGH MOLECULAR WEIGHT COMPOUNDS | ORYXE (US) | 2006-04-20 | — | — | WO | disclosed |