Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203467 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL11195651 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL31245817 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL1991184 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL9583659 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL9385481 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL965454 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL11196574 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL18641608 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 | |
| SCHEMBL1356564 | 1.00 | CA2 (0.57) | CA2GPR84GRIK1GRIK2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144366-B1 | 3,4-DISUBSTITUTED ACYLANILIDE DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA INC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1144366-A3 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2003-06-04 | — | — | EP | disclosed |
| CN-1416416-A | Androgen receptor suppressors in treatment of hirsutism,acne and androgenetic alopecia | BIOPHYSICA INC (US) | 2003-05-07 | — | — | CN | disclosed |
| WO-2001058855-A9 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA INC (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6472415-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2002-10-29 | — | — | US | disclosed |
| EP-1144366-A2 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2001058855-A1 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC (US) | 2001-08-16 | — | — | WO | disclosed |
| US-6184249-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2001-02-06 | — | — | US | disclosed |
| WO-2000037430-A2 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2000-06-29 | — | — | WO | disclosed |