Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | PNP | P00491 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxyadenosine SCHEMBL5982298 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL19877 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL5982291 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL12222478 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL193181 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL23982174 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL532825 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL593935 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL21637036 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 | |
| Deoxyadenosine SCHEMBL12222447 | 1.00 | HIF1A (0.71) | HIF1ASMN1; SMN2PNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350292-B1 | Process for preparing 2'-deoxy-beta-adenosine | JAPAN TOBACCO INC (JP) | 1994-05-04 | — | — | EP | claimed |
| US-5262531-A | Process for preparing 2'-deoxy-β-adenosine | JAPAN TOBACCO, INC. (JP) | 1993-11-16 | — | — | US | claimed |
| EP-0350292-A2 | Process for preparing 2'-deoxy-beta-adenosine | Japan Tobacco Inc. (JP) | 1990-01-10 | — | — | EP | claimed |
| JP-2017199-A | — | — | None | — | — | JP | disclosed |
| EP-1554298-A4 | PROCESS FOR THE PREPARATION OF 9-BETA-ANOMERIC NUCLEOSIDE ANALOGS | ASH STEVENS INC (US) | 2007-09-26 | — | — | EP | disclosed |
| EP-1554298-A1 | PROCESS FOR THE PREPARATION OF 9-BETA-ANOMERIC NUCLEOSIDE ANALOGS | ASH STEVENS, INC. (US) | 2005-07-20 | — | — | EP | disclosed |
| US-6884880-B2 | Process for the preparation of 9-β-anomeric nucleoside analogs | ASH STEVENS, INC. (US) | 2005-04-26 | — | — | US | disclosed |
| WO-2004018490-A1 | PROCESS FOR THE PREPARATION OF 9-BETA-ANOMERIC NUCLEOSIDE ANALOGS | ASH STEVENS, INC. (US) | 2004-03-04 | — | — | WO | disclosed |
| US-20040039190-A1 | Process for the preparation of 9-beta-anomeric nucleoside analogs | ASH STEVENS, INC. | 2004-02-26 | — | — | US | disclosed |
| EP-0350292-B1 | Process for preparing 2'-deoxy-beta-adenosine | JAPAN TOBACCO INC (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5262531-A | Process for preparing 2'-deoxy-β-adenosine | JAPAN TOBACCO, INC. (JP) | 1993-11-16 | — | — | US | disclosed |
| JP-H0217199-A | PRODUCTION OF 2'-DEOXY-BETA-ADENOSINE | JAPAN TOBACCO INC | 1990-01-22 | — | — | JP | disclosed |
| EP-0350292-A2 | Process for preparing 2'-deoxy-beta-adenosine | Japan Tobacco Inc. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4760137-A | Method for the production of 2'-deoxyadenosine compounds | BRIGHAM YOUNG UNIVERSITY (US) | 1988-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039190-A1 | Process for the preparation of 9-beta-anomeric nucleoside analogs | DPYD, SLC29A2, GALE | HIF1A 1549/4885SMN1; SMN2 1155/4885PNP 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.