Deoxyadenosine

Deoxyadenosine

SCHEMBL193181

Nc1ncnc2c1ncn2[C@H]1CC(O)[C@@H](CO)O1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.71
SMN1; SMN2 Q16637 2/20 0.70
PNP P00491 1/20 0.70
LMNA P02545 1/20 0.70
TP53 P04637 1/20 0.70
HTT P42858 1/20 0.70
PDE4D Q08499 1/20 0.70
PDE3A Q14432 1/20 0.70
RXFP1 Q9HBX9 1/20 0.70
ADORA3 P0DMS8 3/20 0.63
DPP4 P27487 1/20 0.63
MEN1 O00255 1/20 0.63
SLC28A1 O00337 1/20 0.63
MAP3K7 O43318 1/20 0.63
SLC28A2 O43868 1/20 0.63
GAPDH P04406 1/20 0.63
MAPK1 P28482 1/20 0.63
ADORA2A P29274 1/20 0.63
ADORA2B P29275 1/20 0.63
ADORA1 P30542 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyadenosine SCHEMBL532825 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL12222478 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL593935 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL12222447 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL5982298 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL23982174 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL5982291 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL19506291 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL21637036 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53
Deoxyadenosine SCHEMBL19877 1.00 HIF1A (0.71) HIF1ASMN1; SMN2PNPLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
WO-2025132708-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF HUNTINGTON'S DISEASE PROQR THERAPEUTICS II B.V. (NL) 2025-06-26 WO claimed
US-12319916-B2 Modulation of gene transcription using antisense oligonucleotides targeting regulatory RNAs CAMP4 THERAPEUTICS CORPORATION (US) 2025-06-03 US claimed
WO-2025104239-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CLASSIC GALACTOSEMIA PROQR THERAPEUTICS II B.V. (NL) 2025-05-22 WO claimed
EP-4555086-A1 OLIGONUCLEOTIDES FOR ADAR-MEDIATED RNA EDITING AND USE THEREOF ProQR Therapeutics II B.V. (NL) 2025-05-21 EP claimed
US-20240336924-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2024-10-10 US claimed
US-20240191231-A1 SPINAL MUSCULAR ATROPHY (SMA) TREATMENT VIA TARGETING OF SMN2 SPLICE SITE INHIBITORY SEQUENCES UNIV MASSACHUSETTS (US) 2024-06-13 US claimed
WO-2024013361-A1 OLIGONUCLEOTIDES FOR ADAR-MEDIATED RNA EDITING AND USE THEREOF PROQR THERAPEUTICS II B.V. (NL) 2024-01-18 WO claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
EP-3286338-B1 AMPLIFICATION WITH PRIMERS OF LIMITED NUCLEOTIDE COMPOSITION Atila Biosystems Incorporated (US) 2023-11-01 EP claimed
US-5639603-A PLURALITY OF DIFFERENT MEMBERS, EACH MEMBER COMPRISING SOLID SUPPORT, MULTIPLE COPIES OF COMPOUND BOUND TO EACH OF THE SUPPORTS; TAGGING, CLEAVING COMPOUNDS AFFYMAX TECHNOLOGIES N.V. (AN) 1997-06-17 US claimed
EP-0726906-A1 SYNTHESIZING AND SCREENING MOLECULAR DIVERSITY AFFYMAX TECHNOLOGIES N.V. (AN) 1996-08-21 EP claimed
WO-1995012608-A1 SYNTHESIZING AND SCREENING MOLECULAR DIVERSITY AFFYMAX TECHNOLOGIES N.V. (AN) 1995-05-11 WO claimed
EP-0420862-B1 PHARMACEUTICAL COMPOSITION CONTAINING DEOXYRIBONUCLEOSIDES FOR WOUND HEALING PRO NEURON INC (US) 1993-11-24 EP claimed
EP-0203959-B1 NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION LIFE TECHNOLOGIES, INC. (US) 1992-09-09 EP claimed
WO-1991019730-A1 RNA HYDROLYSIS/CLEAVAGE MONSANTO COMPANY (US) 1991-12-26 WO claimed
EP-0173059-B1 METHOD FOR THE PRODUCTION OF 2'-DEOXYADENOSINE COMPOUNDS BRIGHAM YOUNG UNIVERSITY (US) 1989-11-29 EP claimed
EP-0203959-A4 NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION. LIFE TECHNOLOGIES INC (US) 1989-08-09 EP claimed
EP-0203959-A1 NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION. LIFE TECHNOLOGIES INC (US) 1986-12-10 EP claimed
WO-1986002929-A1 NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION LIFE TECHNOLOGIES, INC. (US) 1986-05-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336924-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CPS1, CTPS1, CTPS2 HIF1A 2083/4885SMN1; SMN2 1618/4885PNP 829/4885
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT HIF1A 886/4885SMN1; SMN2 58/4885PNP 688/4885
US-12319916-B2 Modulation of gene transcription using antisense oligonucleotides targeting regulatory RNAs CPS1, CTPS1, CTPS2 HIF1A 2083/4885SMN1; SMN2 1618/4885PNP 829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.