Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490488 | 0.82 | KMT2A (0.74) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL5171337 | 0.80 | POLB (0.65) | KMT2AMEN1GAASMN1; SMN2HDAC1 | |
| SCHEMBL5088801 | 0.79 | EPHX2 (0.60) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL5160350 | 0.79 | GAA (0.55) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL4908980 | 0.78 | KMT2A (0.82) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL5175851 | 0.78 | CXCR4 (0.63) | KMT2AMEN1GAAPOLBRAB9A | |
| Difenpiramide SCHEMBL23833 | 0.76 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL29270879 | 0.76 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| Difenpiramide SCHEMBL29238669 | 0.76 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL19555122 | 0.76 | KMT2A (0.77) | KMT2AMEN1SLC6A2SLC6A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | disclosed |