Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 2/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.56 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.56 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908980 | 0.87 | KMT2A (0.82) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| Difenpiramide SCHEMBL29238669 | 0.85 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| Difenpiramide SCHEMBL23833 | 0.85 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL6490488 | 0.85 | KMT2A (0.74) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL1767708 | 0.84 | KMT2A (0.72) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL28194116 | 0.81 | KMT2A (0.68) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL4575591 | 0.81 | KMT2A (0.68) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL6492795 | 0.80 | POLB (0.67) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL933299 | 0.79 | RAB9A (0.74) | KMT2AMEN1RAB9ANPC1TP53 | |
| SCHEMBL31240687 | 0.78 | RIOK2 (0.67) | KMT2AMEN1RAB9ANPC1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114533731-B | Application of aminopyridine derivative in preparation of muscular dystrophy inhibitor | 上海大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-114533731-B | Application of aminopyridine derivative in preparation of muscular dystrophy inhibitor | 上海大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-114533731-A | Application of aminopyridine derivative in preparation of muscular atrophy inhibitor | 上海大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114533731-A | Application of aminopyridine derivative in preparation of muscular atrophy inhibitor | 上海大学 | 2022-05-27 | — | — | CN | disclosed |