Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6056359 | 0.91 | SPHK1 (0.57) | TP53SPHK1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL2047075 | 0.89 | SPHK1 (0.55) | TP53SPHK1S1PR2S1PR1S1PR3 | |
| Sulfuric Acid SCHEMBL3890459 | 0.81 | TP53 (0.59) | TP53SPHK1GPR84FFAR1 | |
| Sulfuric Acid SCHEMBL3896231 | 0.81 | TP53 (0.59) | TP53SPHK1GPR84FFAR1 | |
| Sulfuric Acid SCHEMBL28354719 | 0.81 | TP53 (0.69) | TP53SPHK1S1PR2S1PR1S1PR3 | |
| Sulfuric Acid SCHEMBL27829023 | 0.81 | TP53 (0.69) | TP53SPHK1S1PR2S1PR1S1PR3 | |
| Sulfuric Acid SCHEMBL20515499 | 0.81 | TP53 (0.69) | TP53SPHK1S1PR2S1PR1S1PR3 | |
| Sulfuric Acid SCHEMBL16611550 | 0.81 | TP53 (0.69) | TP53SPHK1S1PR2S1PR1S1PR3 | |
| Tetradecane SCHEMBL99243 | 0.80 | TP53 (0.68) | TP53SPHK1OPRM1CYP2D6LMNA | |
| Sulfuric Acid SCHEMBL28958102 | 0.79 | TP53 (0.62) | TP53SPHK1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437119-B1 | EXTERNAL PREPARATION CONTAIINING GALLIC ACID DERIVATIVES | LION CORP (JP) | 2007-08-15 | — | — | EP | disclosed |
| US-20040247551-A1 | External preparation | LION CORPORATION (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1437119-A1 | EXTERNAL PREPARATION | Lion Corporation (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247551-A1 | External preparation | GANAB, GANC, EEA1 | OPRM1 2428/4885TP53 3357/4885SPHK1 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.