Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 13/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183286 | 1.00 | BDKRB1 (0.42) | BDKRB1TRPV1HSD17B2 | |
| SCHEMBL29920592 | 0.84 | TRPV1 (0.48) | TRPV1HSD17B2 | |
| SCHEMBL20053921 | 0.84 | HSD17B2 (0.41) | TRPV1HSD17B2 | |
| SCHEMBL16814170 | 0.84 | AAK1 (0.41) | TRPV1HSD17B2 | |
| SCHEMBL5505139 | 0.83 | BDKRB1 (0.44) | BDKRB1TRPV1HSD17B2 | |
| SCHEMBL12731042 | 0.82 | CTSD (0.45) | TRPV1 | |
| SCHEMBL31040889 | 0.82 | TRPV1 (0.53) | BDKRB1TRPV1HSD17B2 | |
| SCHEMBL7986840 | 0.82 | BRD4 (0.48) | TRPV1 | |
| SCHEMBL29264385 | 0.82 | BRD4 (0.48) | TRPV1 | |
| SCHEMBL24838463 | 0.81 | HSD17B2 (0.39) | BDKRB1TRPV1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799637-A1 | SUBSTITUTED SULFONAMIDOPROPIONAMIDES AND METHODS OF USE | Amgen, Inc (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006036664-A1 | SUBSTITUTED SULFONAMIDOPROPIONAMIDES AND METHODS OF USE | AMGEN INC. (US) | 2006-04-06 | — | — | WO | disclosed |