Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.67 |
| ▸ | NCS1 | P62166 | 1/20 | 0.64 |
| ▸ | ACP1 | P24666 | 3/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.60 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.60 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.60 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.60 |
| ▸ | SCD | O00767 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287819 | 1.00 | CSNK1D (0.67) | CSNK1DNCS1ACP1PTPN7PTPN12 | |
| SCHEMBL17287822 | 0.83 | CSNK1D (0.75) | CSNK1DNCS1ACP1PTPN7PTPN12 | |
| SCHEMBL4244535 | 0.82 | CSNK1D (0.73) | CSNK1DNCS1ACP1PTPN7PTPN12 | |
| SCHEMBL13949524 | 0.80 | CSNK1D (1.00) | CSNK1DNCS1ACP1PTPN7PTPN12 | |
| SCHEMBL7362397 | 0.79 | HPGD (0.51) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17287798 | 0.78 | CSNK1D (1.00) | CSNK1DNCS1ACP1PTPN7PTPN12 | |
| SCHEMBL5183402 | 0.77 | MRE11 (0.55) | MEN1KMT2APOLBMAPT | |
| SCHEMBL4945628 | 0.76 | CSNK1D (0.60) | CSNK1DNCS1ACP1PTPN7PTPN12 | |
| SCHEMBL5184192 | 0.76 | CCNE1 (0.53) | SMN1; SMN2MEN1KMT2APOLBMAPT | |
| SCHEMBL31078931 | 0.75 | GAA (0.71) | CSNK1DACP1SCDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758920-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005113579-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |