Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | CMA1 | P23946 | 6/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.36 |
| ▸ | PFKFB4 | Q16877 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684098 | 0.82 | SLC2A1 (0.42) | PPARGPPARDPPARACMA1SLC2A1 | |
| SCHEMBL3695623 | 0.73 | PPARG (0.42) | PPARGPPARDPPARACMA1SLC2A1 | |
| SCHEMBL3691091 | 0.68 | PPARD (0.43) | PPARGPPARDPPARACMA1SLC2A1 | |
| SCHEMBL3690029 | 0.68 | PPARG (0.40) | PPARGPPARDPPARACMA1SLC2A1 | |
| SCHEMBL3689304 | 0.67 | PFKFB3 (0.41) | PPARGPPARDPPARACMA1SLC2A1 | |
| SCHEMBL3683554 | 0.67 | PPARD (0.44) | PPARGPPARDPPARACMA1PFKFB3 | |
| SCHEMBL5330312 | 0.66 | CMA1 (0.52) | CMA1PFKFB3PFKFB4HTR1ADRD2 | |
| SCHEMBL3683400 | 0.66 | PPARD (0.43) | PPARGPPARDPPARACMA1PFKFB3 | |
| SCHEMBL7018250 | 0.65 | PFKFB3 (0.53) | CMA1PFKFB3PFKFB4 | |
| SCHEMBL3689885 | 0.64 | SLC2A1 (0.40) | CMA1SLC2A1PFKFB3PFKFB4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |