Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 7/20 | 0.53 |
| ▸ | PFKFB4 | Q16877 | 7/20 | 0.53 |
| ▸ | CMA1 | P23946 | 7/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679315 | 0.81 | PFKFB3 (0.44) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL3695829 | 0.81 | CMA1 (0.46) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL2226181 | 0.78 | NPSR1 (0.60) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6712744 | 0.76 | NPSR1 (0.59) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL1548591 | 0.76 | NPSR1 (0.62) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL337593 | 0.76 | NPSR1 (0.62) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL13696908 | 0.76 | NPSR1 (0.62) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL7012927 | 0.74 | KEAP1 (0.42) | NPSR1ALDH1A1 | |
| SCHEMBL3679313 | 0.73 | PFKFB3 (0.43) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 | |
| SCHEMBL3695828 | 0.73 | CMA1 (0.43) | PFKFB3PFKFB4CMA1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | PFKFB3 2877/4885PFKFB4 2630/4885CMA1 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.