Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 18/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186715 | 0.86 | FBP1 (0.53) | FBP1PPARGPPARA | |
| SCHEMBL6743475 | 0.86 | FBP1 (0.53) | FFAR4FFAR1FBP1PPARGPPARA | |
| SCHEMBL22005942 | 0.85 | FBP1 (0.57) | FBP1PPARGPPARA | |
| SCHEMBL4681712 | 0.84 | FBP1 (0.56) | FBP1PPARGPPARA | |
| SCHEMBL5186522 | 0.84 | FBP1 (0.51) | FFAR4FFAR1FBP1PPARGPPARA | |
| SCHEMBL21188309 | 0.84 | FBP1 (0.54) | FFAR4FBP1PPARGPPARA | |
| SCHEMBL1549215 | 0.83 | FBP1 (0.55) | FBP1PPARGPPARA | |
| SCHEMBL27350601 | 0.83 | FFAR4 (0.45) | FFAR4FFAR1FBP1PPARGPPARA | |
| SCHEMBL4681849 | 0.83 | FBP1 (0.55) | FBP1PPARGPPARA | |
| Acetic Acid SCHEMBL4693562 | 0.82 | FBP1 (0.52) | FBP1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863772-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007028424-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-15 | — | — | WO | disclosed |