SCHEMBL51869

SCHEMBL51869

Oc1cccc(-c2ccccc2)c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 10/20 0.84
HSD17B2 P37059 10/20 0.84
CYP3A4 P08684 3/20 0.84
CYP2C9 P11712 2/20 0.84
ESR1 P03372 5/20 0.60
ESR2 Q92731 4/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2D6 P10635 1/20 0.60
CYP2B6 P20813 1/20 0.60
CYP2C19 P33261 1/20 0.60
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ALDH1A1 P00352 2/20 0.58
LMNA P02545 2/20 0.58
HSD17B10 Q99714 2/20 0.58
CA12 O43570 1/20 0.58
CA2 P00918 1/20 0.58
CA5A P35218 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356013 1.00 HSD17B1 (0.84) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL19845791 0.97 HSD17B1 (0.80) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL2682114 0.97 HSD17B1 (0.90) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Hydrochloric Acid SCHEMBL5069276 0.97 HSD17B1 (0.80) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Hydrochloric Acid SCHEMBL30534237 0.97 HSD17B1 (0.80) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL28704509 0.97 HSD17B1 (0.80) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL29832647 0.97 HSD17B1 (0.90) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL11819204 0.97 HSD17B1 (0.80) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL14973515 0.97 HSD17B1 (0.80) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL28363523 0.97 HSD17B1 (0.79) HSD17B1HSD17B2CYP3A4CYP2C9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5690 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-20250304746-A1 POLYOL BLOCK COPOLYMER, COMPOSITIONS AND PROCESSES THEREFOR ECONIC TECHNOLOGIES LTD. (GB) 2025-10-02 US claimed
US-12336537-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2025-06-24 US claimed
CN-119912502-A Purification method of konjak alkaloid and application of konjak alkaloid in pest control 南京荣芋科技有限公司 2025-05-02 CN claimed
CN-114099538-B Application of rabdosia amethystoides crude polysaccharide 上海医药集团股份有限公司 2025-04-08 CN claimed
US-20250098677-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 US claimed
CN-119552660-A Hafnium oxide etching solution and preparation method thereof 湖北兴福电子材料股份有限公司 2025-03-04 CN claimed
CN-119470284-A Method for detecting sequential content of sargassum fusiforme marker active component group 浙江石原金牛生物科技有限公司 2025-02-18 CN claimed
US-20250040552-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-02-06 US claimed
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-01-14 US claimed
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US claimed
US-5238776-A Improved thermal properties, etch resistance, high speed SHIPLEY COMPANY INC. (US) 1993-08-24 US claimed
EP-0529936-A1 Epoxy resin compositions MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-03 EP claimed
CN-1064683-A New beta-amino-alpha-hydroxycarboxylic acids and uses thereof SANKYO CO (JP) 1992-09-23 CN claimed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP claimed
US-5130410-A Condencing a bishydroxymethyl phenol with a reactive phenol in the absence of an aldehyde to form an alternating copolymer and reacting in the presence of an aromatic aldehyde SHIPLEY COMPANY INC. (US) 1992-07-14 US claimed
EP-0491045-A1 NOVEL PHENOL/ARALKYL RESIN, PRODUCTION THEREOF, AND EPOXY RESIN COMPOSITION CONTAINING THE SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-06-24 EP claimed
US-4533766-A Process for the production of dihydroxybenzenes DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-08-06 US claimed
WO-1980000791-A1 B-GLUCURONIDASE ACTIVITY AND/OR PH-DEPENDENT PHARMACEUTICALS AND THEIR METHODS OF PRODUCTION AND USE FOR SELECTIVE TREATMENT OF DISEASES SCHWIMMER A (US) 1980-05-01 WO claimed
US-3993700-A AQUEOUS CAUSTIC SOLUTION THE DOW CHEMICAL COMPANY (US) 1976-11-23 US claimed