Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.54 |
| ▸ | PPARA | Q07869 | 18/20 | 0.54 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188275 | 0.93 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL5188301 | 0.92 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL5186528 | 0.89 | PPARA (0.47) | PPARDPPARAPPARG | |
| SCHEMBL5187697 | 0.86 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL5937517 | 0.85 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL5186646 | 0.85 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL5187765 | 0.84 | PPARD (0.52) | PPARDPPARAPPARG | |
| SCHEMBL1375255 | 0.84 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL5188784 | 0.84 | PPARD (0.54) | PPARDPPARAPPARG | |
| SCHEMBL5186525 | 0.82 | PPARD (0.46) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863772-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-12-12 | — | — | EP | claimed |
| WO-2007028424-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-15 | — | — | WO | claimed |
| EP-1863772-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007028424-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-15 | — | — | WO | disclosed |