⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262111 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL866984 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL7589647 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL2081 | 1.00 | — | — | |
| SCHEMBL15121489 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL16694147 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL5429 | 1.00 | — | — | |
| SCHEMBL3030900 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL21831576 | 1.00 | ALDH1A1 (0.36) | — | |
| SCHEMBL447244 | 1.00 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5517 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396181-A1 | 2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE P2X7 ANTAGONISTS | Breye Therapeutics ApS (DK) | 2024-07-10 | — | — | EP | claimed |
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| WO-2024094125-A1 | LIPID COMPOUNDS, LIPID NANOPARTICLES, AND PHARMACEUTICAL COMPOSITIONS | Shanghai Circode Biomed Co., Ltd. (CN) | 2024-05-10 | — | — | WO | claimed |
| CN-117881675-A | 2, 4-dihydro-3H-1, 2, 4-triazol-3-one P2X7 antagonists | 布雷耶疗法有限公司 | 2024-04-12 | — | — | CN | claimed |
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | claimed |
| EP-3544601-B1 | A COMPOSITION COMPRISING A BENZAMIDE AND A TNFRSF AGONIST BINDING TO 4-1BB OR GITR, AND THE USE THEREOF IN THE TREATMENT OF CANCER. | TRANSLATIONAL DRUG DEV LLC (US) | 2024-03-20 | — | — | EP | claimed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | claimed |
| CN-116903480-A | Method for preparing beta-enaminone based on sulfoxide and aldoxime and beta-enaminone | 盐城师范学院 | 2023-10-20 | — | — | CN | claimed |
| US-20230295201-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2023-09-21 | — | — | US | claimed |
| CN-110944987-B | Herbicidal 3-substituted lactams | FMC公司 | 2023-09-15 | — | — | CN | claimed |
| EP-0101925-B1 | SUBSTITUTED AZOLYLVINYL KETONES AND CARBINOLS | BAYER AG (DE) | 1986-11-26 | — | — | EP | claimed |
| US-4603140-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-29 | — | — | US | claimed |
| EP-0179015-A1 | 7-(Aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-04-23 | — | — | EP | claimed |
| EP-0103798-A2 | Substituted azolylalkyl-t.butyl ketones and carbinols | BAYER AG (DE) | 1984-03-28 | — | — | EP | claimed |
| EP-0101925-A1 | Substituted azolylvinyl ketones and carbinols | BAYER AG (DE) | 1984-03-07 | — | — | EP | claimed |
| US-4426389-A | BACTERICIDES, ENZYME INHIBITORS | BEECHAM GROUP LIMITED (GB) | 1984-01-17 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4088772-A | TRANQUILIZERS, ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-05-09 | — | — | US | claimed |
| US-4077977-A | Ethenoanthracenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-03-07 | — | — | US | claimed |