SCHEMBL5188673

SCHEMBL5188673

Oc1ccn2ncnc2n1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.45
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAP4K4 O95819 2/20 0.33
EGFR P00533 1/20 0.32
FLT1 P17948 1/20 0.32
FLT4 P35916 1/20 0.32
KDR P35968 1/20 0.32
GAA P10253 1/20 0.31
CYP2C19 P33261 1/20 0.31
MAPK1 P28482 1/20 0.31
KCNH2 Q12809 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9372254 0.75 KDM4E (0.45) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL362643 0.75 PDE10A (0.45) PDE10AKDM4EALDH1A1MAP4K4EGFR
SCHEMBL23030808 0.73 KDM4E (0.41) PDE10AKDM4EALDH1A1
SCHEMBL9933877 0.71 PDE10A (0.41) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL23143432 0.68 PIK3CD (0.55) PDE10AKDM4EALDH1A1MAP4K4CYP2C19
SCHEMBL12761233 0.67
SCHEMBL31553111 0.65 PIK3CD (0.31)
SCHEMBL1440869 0.65 DYRK1A (0.49) PDE10A
SCHEMBL30512173 0.64 DYRK1A (0.47) PDE10A
SCHEMBL7103183 0.62 ALDH1A1 (0.46) KDM4EALDH1A1GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208346-A2 Diffusion transfer reversal process AGFA-GEVAERT N.V. (BE) 1987-01-14 EP claimed
EP-1016902-B1 Color photographic element EASTMAN KODAK CO (US) 2007-06-06 EP disclosed
US-6455242-B1 MIXTURE OF LIGHT SENSITIVE MATERIAL AND LIGHT INSENSITIVE MATERIAL EASTMAN KODAK COMPANY 2002-09-24 US disclosed
US-20020042033-A1 Color photographic element containing speed improving compound QUALEX INC. 2002-04-11 US disclosed
US-6319660-B1 LIGHT SENSITIVITY, SPEED EASTMAN KODAK COMPANY 2001-11-20 US disclosed
US-6316177-B1 COLOR SILVER HALIDE PHOTOGRAPHIC ELEMENT OR NONSILVER LIGHT INSENSITIVE LAYER WITH HETEROCYCLIC POLYMER EASTMAN KODAK COMPANY 2001-11-13 US disclosed
EP-1143291-A2 Color photographic element containing speed-improving polymer EASTMAN KODAK COMPANY (US) 2001-10-10 EP disclosed
EP-1016902-A2 Color photographic element EASTMAN KODAK COMPANY (US) 2000-07-05 EP disclosed
EP-0208346-A2 Diffusion transfer reversal process AGFA-GEVAERT N.V. (BE) 1987-01-14 EP disclosed
US-4358530-A SUPPORTED NONSILVER PHOTOGRAPHIC LAYER HAVING A SILVER HALIDE EMULSION COATING CONTAINING A PHENYL HYDRAZIDE FUJI PHOTO FILM CO., LTD. (JP) 1982-11-09 US disclosed