Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | HTT | P42858 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58070 | 0.87 | ALDH1A1 (0.49) | MAPTHTTPOLBALDH1A1MITF | |
| SCHEMBL5188985 | 0.86 | ALDH1A1 (0.40) | MAPTHTTPOLBALDH1A1MITF | |
| SCHEMBL58073 | 0.85 | MAPT (0.51) | MAPTHTTPOLBALDH1A1NPSR1 | |
| SCHEMBL4194009 | 0.73 | ALDH1A1 (0.50) | MAPTHTTPOLBALDH1A1MITF | |
| SCHEMBL4189866 | 0.72 | MAPT (0.46) | MAPTHTTPOLBALDH1A1NPSR1 | |
| SCHEMBL16324474 | 0.71 | ALDH1A1 (0.68) | MAPTPOLBALDH1A1MITFSMN1; SMN2 | |
| SCHEMBL12901284 | 0.70 | ALDH1A1 (0.43) | POLBALDH1A1MITFSOS1PKM | |
| SCHEMBL31437774 | 0.67 | ALDH1A1 (0.49) | MAPTPOLBALDH1A1MITFLMNA | |
| SCHEMBL5180079 | 0.67 | MAPT (0.36) | MAPTHTTPOLBALDH1A1 | |
| SCHEMBL3466332 | 0.65 | ALDH1A1 (0.46) | MAPTPOLBALDH1A1MITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794132-A2 | PROCESS FOR PRODUCTION OF 2-CHLORO-4-NITROIMIDAZOLE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006035960-A2 | PROCESS FOR PRODUCTION OF 2-CHLORO-4-NITROIMIDAZOLE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |