Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164994 | 0.88 | ADRB2 (0.55) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL4593784 | 0.87 | ADRB2 (0.57) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL5163988 | 0.85 | ADRB2 (0.56) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL5190236 | 0.83 | ADRB2 (0.52) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL5164807 | 0.83 | ADRB2 (0.56) | ADRB2ADRB1 | |
| SCHEMBL5165194 | 0.83 | ADRB2 (0.65) | ADRB2ADRB1 | |
| SCHEMBL3649801 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL5192822 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| SCHEMBL3634485 | 0.81 | ADRB2 (0.55) | ADRB2ADRB1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL4593598 | 0.81 | ADRB2 (0.56) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809293-A2 | AEROSOL FORMULATION FOR INHALATION OF BETA AGONISTS | Boehringer Ingelheim International GmbH (DE) | 2007-07-25 | — | — | EP | disclosed |
| EP-1781298-A1 | PHARMACEUTICAL COMBINATIONS CONTAINING BENZOXAZINE FOR TREATING RESPIRATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2005110421-A2 | AEROSOL FORMULATION FOR INHALATION OF BETA AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005102349-A1 | PHARMACEUTICAL COMBINATIONS CONTAINING BENZOXAZINE FOR TREATING RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |