Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.61 |
| ▸ | TUBB | P07437 | 4/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.61 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.61 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.61 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.61 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.61 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.61 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.61 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.61 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.61 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.61 |
| ▸ | PDE4A | P27815 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5607052 | 0.99 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL5191040 | 0.90 | PDE4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL5193802 | 0.88 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5607539 | 0.86 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5192285 | 0.85 | PDE4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5191999 | 0.85 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL5190935 | 0.85 | PDE4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5191775 | 0.84 | TUBB4A (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL5189397 | 0.84 | TUBB4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27616021 | 0.83 | TUBB1 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799634-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006026747-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |