Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389917 | 0.90 | GPR119 (0.64) | GPR119 | |
| SCHEMBL389360 | 0.86 | GPR119 (0.68) | GPR119 | |
| SCHEMBL3681418 | 0.84 | GPR119 (0.65) | GPR119 | |
| SCHEMBL3164609 | 0.83 | GPR119 (0.58) | GPR119 | |
| SCHEMBL3163892 | 0.81 | GPR119 (0.61) | GPR119 | |
| SCHEMBL5046374 | 0.81 | GPR119 (0.54) | GPR119 | |
| SCHEMBL387987 | 0.80 | GPR119 (0.65) | GPR119 | |
| SCHEMBL1070010 | 0.79 | GPR119 (0.62) | GPR119 | |
| SCHEMBL388590 | 0.78 | GPR119 (0.64) | GPR119 | |
| SCHEMBL389106 | 0.77 | GPR119 (0.64) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758565-A2 | COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL | Arena Pharmaceuticals, Inc. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006076231-A2 | COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL | ARENA PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |