Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897817 | 0.92 | GPR119 (0.63) | GPR119CYP2C9 | |
| SCHEMBL5189058 | 0.92 | GPR119 (0.63) | GPR119CYP2C9 | |
| SCHEMBL5188085 | 0.91 | GPR119 (0.58) | GPR119CYP2C9 | |
| SCHEMBL2406799 | 0.91 | GPR119 (0.61) | GPR119CYP2C9 | |
| SCHEMBL3735863 | 0.90 | GPR119 (0.60) | GPR119CYP2C9 | |
| SCHEMBL2405135 | 0.90 | GPR119 (0.62) | GPR119CYP2C9 | |
| SCHEMBL2464079 | 0.89 | GPR119 (0.59) | GPR119CYP2C9 | |
| SCHEMBL2402781 | 0.88 | GPR119 (0.60) | GPR119CYP2C9 | |
| SCHEMBL2403336 | 0.87 | GPR119 (0.57) | GPR119CYP2C9 | |
| SCHEMBL2407525 | 0.87 | GPR119 (0.59) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758565-A2 | COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL | Arena Pharmaceuticals, Inc. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006076231-A2 | COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL | ARENA PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |