Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048777 | 0.95 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Benzoyl Peroxide SCHEMBL32689642 | 0.91 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Ethyl Benzoate SCHEMBL27869298 | 0.91 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Acetophenone SCHEMBL25285894 | 0.90 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL15425 | 0.89 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Terephthalic Acid SCHEMBL29135372 | 0.89 | SMN1; SMN2 (0.66) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL5190217 | 0.89 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Benzoic Acid SCHEMBL29135370 | 0.89 | SMN1; SMN2 (0.66) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Acetic Acid SCHEMBL26103642 | 0.87 | ALDH1A1 (0.65) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL11211951 | 0.87 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813654-A1 | Radiation curable conductive ink and manufacturing method for using the same | Yang, Yung-Shu (TW) | 2007-08-01 | — | — | EP | disclosed |