⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7058874 | 0.98 | ALOX5 (0.55) | — | |
| SCHEMBL3878505 | 0.80 | — | — | |
| SCHEMBL9868561 | 0.80 | — | — | |
| SCHEMBL2100379 | 0.79 | ALOX5 (0.53) | — | |
| SCHEMBL9135489 | 0.79 | KMT2A (0.44) | — | |
| SCHEMBL4197024 | 0.78 | — | — | |
| SCHEMBL4197018 | 0.78 | — | — | |
| SCHEMBL11608550 | 0.78 | — | — | |
| SCHEMBL10870261 | 0.78 | — | — | |
| SCHEMBL11551769 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794437-B | Synthetic method of 2- (3-furyl) acetamide compound | 河南师范大学 | 2022-11-15 | — | — | CN | claimed |
| CN-1278166-A | Mixtures of enanthiomers of aminocyclohexylamides to produce simultaneous analgesia with local anaesthesia or antiarrhythmia | NORTRAN PHARMACEUTICALS INC (CA) | 2000-12-27 | — | — | CN | claimed |
| WO-1999016431-A1 | MIXTURES OF ENANTIOMERS OF AMINOCYCLOHEXYLAMIDES TO PRODUCE SIMULTANEOUS ANALGESIA WITH LOCAL ANAESTHESIA OR ANTIARRHYTHMIA | NORTRAN PHARMACEUTICALS INC. (CA) | 1999-04-08 | — | — | WO | claimed |
| CN-108794437-B | Synthetic method of 2- (3-furyl) acetamide compound | 河南师范大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-108794437-B | Synthetic method of 2- (3-furyl) acetamide compound | 河南师范大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-108794437-B | Synthetic method of 2- (3-furyl) acetamide compound | 河南师范大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-108794437-A | A kind of synthetic method of 2- (3- furyls) acetamides | 河南师范大学 | 2018-11-13 | — | — | CN | disclosed |
| WO-2013009844-A2 | C-3 SUBSTITUTED BICYCLOOCTANE BASED HIV PROTEASE INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2013-01-17 | — | — | WO | disclosed |
| CN-100398154-C | Remedies for psychoneurosis | TORAY INDUSTRIES (JP) | 2008-07-02 | — | — | CN | disclosed |
| EP-1363925-B8 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2007-04-25 | — | — | EP | disclosed |
| CN-1291717-C | Antipruritic | TORAY INDUSTRIES (JP) | 2006-12-27 | — | — | CN | disclosed |
| EP-0897726-A1 | ANTIPRURITIC AGENT | TORAY INDUSTRIES, INC. (JP) | 1999-02-24 | — | — | EP | disclosed |
| EP-0592490-A4 | AMINO ACID DERIVATIVE ANTICONVULSANT | RES CORP TECHNOLOGIES INC (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0592490-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0019401-B1 | PROCESS FOR PREPARING ENAMINE DERIVATIVES, COMPOUNDS SO PRODUCED AND PROCESS FOR PREPARING A 3-HYDROXY-CEPHALOSPORIN | Lilly Industries Limited (GB) | 1984-03-21 | — | — | EP | disclosed |
| US-4301280-A | Preparation of 3-substituted cephalosporins | LILLY INDUSTRIES LIMITED (GB) | 1981-11-17 | — | — | US | disclosed |
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |
| US-4176231-A | Process for preparing 3-exomethylenecepham sulfoxides | LILLY INDUSTRIES LIMITED (GB) | 1979-11-27 | — | — | US | disclosed |
| US-4159266-A | AZETIDINONE SULFINIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4052387-A | METHOD OF PREPARATION OF 3-METHYLENECEPHAMS | ELI LILLY AND COMPANY (US) | 1977-10-04 | — | — | US | disclosed |