SCHEMBL5190937

SCHEMBL5190937

Cc1cc(CC[N+](C)(C)CC(O)c2cc(O)cc3c2OCC(=O)N3)ccc1F

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 20/20 0.54
ADRB1 P08588 10/20 0.52
CHRM2 P08172 1/20 0.49
HTR1A P08908 1/20 0.49
ADRA2A P08913 1/20 0.49
HTR2A P28223 1/20 0.49
SLC6A4 P31645 1/20 0.49
ADRA1A P35348 1/20 0.49
PTGS2 P35354 1/20 0.49
HTR2B P41595 1/20 0.49
SLC6A3 Q01959 1/20 0.49
PDE4D Q08499 1/20 0.49
KCNH2 Q12809 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634485 0.93 ADRB2 (0.55) ADRB2ADRB1CHRM2HTR1AADRA2A
SCHEMBL5163804 0.90 ADRB2 (0.53) ADRB2ADRB1CHRM2HTR1AADRA2A
SCHEMBL5165823 0.90 ADRB2 (0.52) ADRB2ADRB1CHRM2HTR1AADRA2A
Hydrochloric Acid SCHEMBL4593598 0.89 ADRB2 (0.56) ADRB2ADRB1
SCHEMBL5164994 0.89 ADRB2 (0.55) ADRB2ADRB1CHRM2HTR1AADRA2A
SCHEMBL5165092 0.89 ADRB2 (0.53) ADRB2ADRB1CHRM2HTR1AADRA2A
Hydrochloric Acid SCHEMBL5582900 0.88 ADRB2 (0.68) ADRB2ADRB1
Hydrochloric Acid SCHEMBL4593784 0.88 ADRB2 (0.57) ADRB2ADRB1CHRM2HTR1AADRA2A
SCHEMBL4283475 0.88 ADRB2 (0.63) ADRB2ADRB1CHRM2HTR1AADRA2A
SCHEMBL5164807 0.87 ADRB2 (0.56) ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1809293-A2 AEROSOL FORMULATION FOR INHALATION OF BETA AGONISTS Boehringer Ingelheim International GmbH (DE) 2007-07-25 EP disclosed
WO-2005110421-A2 AEROSOL FORMULATION FOR INHALATION OF BETA AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-24 WO disclosed