Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | LCT | P09848 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | UGCG | Q16739 | 2/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669317 | 0.85 | CYP3A4 (0.44) | FFAR4FFAR1CYP2C19CYP1A2SLC6A4 | |
| SCHEMBL1520992 | 0.81 | IDO1 (0.55) | FFAR4FFAR1CYP2C19 | |
| SCHEMBL20602046 | 0.81 | HRH3 (0.55) | CYP2C19HTR7CYP1A2SLC6A4SLC6A3 | |
| SCHEMBL9291600 | 0.80 | FFAR4 (0.57) | FFAR4FFAR1CYP2C19SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL15709211 | 0.80 | HRH3 (0.54) | CYP2C19HTR7CYP1A2SLC6A4SLC6A3 | |
| SCHEMBL9292754 | 0.79 | CYP2C19 (0.57) | FFAR4FFAR1CYP2C19SLC6A4SLC6A3 | |
| SCHEMBL4667598 | 0.77 | TACR1 (0.60) | FFAR4FFAR1CYP2C19TACR1HTR7 | |
| SCHEMBL28257937 | 0.76 | TACR1 (0.48) | FFAR4FFAR1TACR1HTR7CHRNB2 | |
| SCHEMBL9338655 | 0.76 | TACR1 (0.58) | FFAR4FFAR1TACR1HTR7CHRNB2 | |
| SCHEMBL1559894 | 0.76 | CYP2C19 (0.49) | FFAR4FFAR1CYP2C19HTR7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983222-B1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 2007-11-28 | — | — | EP | disclosed |
| US-6130221-A | ALZHEIMERS | NYMOX CORPORATION (CA) | 2000-10-10 | — | — | US | disclosed |
| WO-1998052898-A9 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 1999-04-01 | — | — | WO | disclosed |