Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.50 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.42 |
| ▸ | CCR7 | P32248 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190620 | 0.89 | CXCR2 (0.65) | CXCR2CCR7 | |
| SCHEMBL5193193 | 0.87 | CXCR2 (0.53) | CXCR2CX3CR1CCR7 | |
| SCHEMBL5190838 | 0.83 | CXCR2 (0.71) | CXCR2CCR7 | |
| SCHEMBL5189197 | 0.83 | CXCR2 (0.71) | CXCR2CCR7 | |
| SCHEMBL3851666 | 0.78 | CXCR2 (0.75) | CXCR2CX3CR1CCR7 | |
| SCHEMBL3851663 | 0.78 | CXCR2 (0.75) | CXCR2CX3CR1CCR7 | |
| SCHEMBL5191014 | 0.78 | CXCR2 (0.49) | CXCR2CX3CR1CCR7 | |
| SCHEMBL5189413 | 0.77 | CXCR2 (0.66) | CXCR2CCR7 | |
| SCHEMBL5190690 | 0.77 | CXCR2 (0.63) | CXCR2CCR7 | |
| SCHEMBL5191298 | 0.75 | CXCR2 (0.69) | CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419158-B1 | PTERIDINONE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | EP | claimed |