Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.53 |
| ▸ | CCR7 | P32248 | 8/20 | 0.47 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191298 | 0.88 | CXCR2 (0.69) | CXCR2CCR7 | |
| SCHEMBL5191087 | 0.87 | CXCR2 (0.50) | CXCR2CCR7CX3CR1 | |
| SCHEMBL5189197 | 0.86 | CXCR2 (0.71) | CXCR2CCR7 | |
| SCHEMBL5190838 | 0.86 | CXCR2 (0.71) | CXCR2CCR7 | |
| SCHEMBL3851663 | 0.81 | CXCR2 (0.75) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3851666 | 0.81 | CXCR2 (0.75) | CXCR2CCR7CX3CR1 | |
| SCHEMBL5191014 | 0.81 | CXCR2 (0.49) | CXCR2CCR7CX3CR1 | |
| SCHEMBL5190666 | 0.80 | CXCR2 (0.65) | CXCR2CCR7 | |
| SCHEMBL6357251 | 0.77 | CXCR2 (0.65) | CXCR2CCR7CX3CR1 | |
| SCHEMBL5189173 | 0.77 | CXCR2 (0.72) | CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419158-B1 | PTERIDINONE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | EP | claimed |