Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13984813 | 0.86 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13986023 | 0.86 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4824587 | 0.84 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL4824599 | 0.84 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL5193830 | 0.82 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL4816638 | 0.77 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4816624 | 0.77 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4816602 | 0.77 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL5284427 | 0.74 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL4818140 | 0.73 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799634-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006026747-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |