SCHEMBL5191128

SCHEMBL5191128

COC(=O)c1cc(O)c(OC2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 4/20 0.55
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA13 Q8N1Q1 1/20 0.53
APP P05067 1/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
POLB P06746 1/20 0.51
SOST Q9BQB4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5181117 0.93 SLC28A3 (0.56) SLC28A3APP
SCHEMBL4378546 0.88 SLC28A3 (0.56) SLC28A3APPPOLB
SCHEMBL4375719 0.88 SLC28A3 (0.56) SLC28A3APPPOLB
SCHEMBL19806793 0.88 PTGS1 (0.63) SLC28A3CA12CA1CA7CA9
SCHEMBL13577089 0.87 USP2 (0.58) SLC28A3MEN1KMT2APOLBSOST
SCHEMBL5181145 0.87 USP2 (0.58) SLC28A3MEN1KMT2APOLBSOST
SCHEMBL5181431 0.87 USP2 (0.58) SLC28A3MEN1KMT2APOLBSOST
SCHEMBL3140292 0.87 USP2 (0.58) SLC28A3MEN1KMT2APOLBSOST
SCHEMBL13576893 0.87 USP2 (0.58) SLC28A3MEN1KMT2APOLBSOST
SCHEMBL14120919 0.86 POLB (0.59) APPPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337162-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC Management LLC (US) 2024-03-20 EP claimed
US-20220362124-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MAN LLC (US) 2022-11-17 US claimed
WO-2022241166-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MANAGEMENT LLC (US) 2022-11-17 WO claimed
US-11298308-B1 Hair bleaching compositions and methods of use ELC MANAGEMENT LLC (US) 2022-04-12 US claimed
EP-4337162-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC Management LLC (US) 2024-03-20 EP disclosed
US-11602497-B2 Hair bleaching compositions and methods of use ELC MANAGEMENT LLC (US) 2023-03-14 US disclosed
WO-2022241166-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MANAGEMENT LLC (US) 2022-11-17 WO disclosed
US-20220362124-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE ELC MAN LLC (US) 2022-11-17 US disclosed
US-11298308-B1 Hair bleaching compositions and methods of use ELC MANAGEMENT LLC (US) 2022-04-12 US disclosed
US-7282520-B2 External preparation LION CORPORATION (JP) 2007-10-16 US disclosed
EP-1437119-B1 EXTERNAL PREPARATION CONTAIINING GALLIC ACID DERIVATIVES LION CORP (JP) 2007-08-15 EP disclosed
US-20040247551-A1 External preparation LION CORPORATION (JP) 2004-12-09 US disclosed
EP-1437119-A1 EXTERNAL PREPARATION Lion Corporation (JP) 2004-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220362124-A1 HAIR BLEACHING COMPOSITIONS AND METHODS OF USE CAT, TYR, GPX1 SLC28A3 1446/4885CA12 1355/4885CA1 1924/4885
US-20040247551-A1 External preparation GANAB, GANC, EEA1 SLC28A3 1003/4885CA12 193/4885CA1 166/4885
US-11602497-B2 Hair bleaching compositions and methods of use CAT, TYR, GPX1 SLC28A3 1446/4885CA12 1355/4885CA1 1924/4885
US-11298308-B1 Hair bleaching compositions and methods of use CAT, TYR, GPX1 SLC28A3 1446/4885CA12 1355/4885CA1 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.