Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefprozil Anhydrous, (E)-. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.98 |
| ▸ | MEN1 | O00255 | 5/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.75 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | ESR1 | P03372 | 1/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.75 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefprozil Anhydrous, (E)- SCHEMBL16072814 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL9177544 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL18814837 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL14108301 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil SCHEMBL37024 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL10801275 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL7586258 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL2901170 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL14064854 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL37023 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727070-A | REACTION WITH KETONE AND FORMATION OF SODIUM SALT | BRISTOL-MYERS COMPANY (US) | 1988-02-23 | — | — | US | claimed |
| US-4694079-A | CRYSTALLINE DIMETHYLFORMAMIDE SOLVATE | BRISTOL-MYERS COMPANY (US) | 1987-09-15 | — | — | US | claimed |
| EP-1809638-A1 | A NOVEL PROCESS FOR PREPARATION OF CEFPROZIL INTERMEDIATE | Hetero Drugs Limited (IN) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006048887-A1 | A NOVEL PROCESS FOR PREPARATION OF CEFPROZIL INTERMEDIATE | HETERO DRUGS LIMITED (IN) | 2006-05-11 | — | — | WO | disclosed |
| CN-1015263-B | PROCESS FOR PREPARATION OF 3-PROPENYL CEPHALOSPORIN SOLVATES | BRISTOL MYERS CO (US) | 1992-01-01 | — | — | CN | disclosed |
| US-4727070-A | REACTION WITH KETONE AND FORMATION OF SODIUM SALT | BRISTOL-MYERS COMPANY (US) | 1988-02-23 | — | — | US | disclosed |
| US-4727070-A | REACTION WITH KETONE AND FORMATION OF SODIUM SALT | BRISTOL-MYERS COMPANY (US) | 1988-02-23 | — | — | US | disclosed |
| US-4699979-A | 7-amino-3-propenylcephalosporanic acid and esters thereof | BRISTOL-MEYERS COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| US-4694079-A | CRYSTALLINE DIMETHYLFORMAMIDE SOLVATE | BRISTOL-MYERS COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| US-4694079-A | CRYSTALLINE DIMETHYLFORMAMIDE SOLVATE | BRISTOL-MYERS COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| US-4619925-A | ANTIBIOTICS FOR GRAMPOSITIVE AND GRAMNEGATIVE BACTERIA | BRISTOL-MYERS COMPANY (US) | 1986-10-28 | — | — | US | disclosed |